Radboudumc
Co-supervisor ESR1 and ESR2
Extracellular Matrix
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Biomaterials
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Collagen
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Glycosaminoglycans
Toin van Kuppevelt, a trained biochemist and cell biologist, is associated professor at the Dept. of Biochemistry of the Radboud university medical center (Radboudumc) in Nijmegen, The Netherlands. He has published ~ 350 papers (H index 58), and has supervised over 35 PhD students. He is involved/coordinates university courses for BSc and MSc students in Medicine, Molecular Life Sciences and Dentistry.
The research of Toin van Kuppevelt focuses on the role of extracellular matrix molecules, notably proteoglycans, in health and disease. Special attention is given to glycosaminoglycans, the sugar moiety of proteoglycans, and their role in regenerative medicine and pathologies. In addition, matrix molecules such as collagen, elastin and glycosaminoglycans are used to construct molecularly-defined scaffolds for tissue engineering and regenerative medicine. The overall aim is to prepare smart scaffolds to generate specific tissues such as skin, cartilage and blood vessels.
Van Kuppevelt has been involved in a number of international grants including projects of EU Biotechnology, Mizutani Foundation for Glycoscience (Japan), Human Frontier Science program, EFRO (European Fund for Regional Development), and four large grants within the EU FP6-Lifescihealth, FP7-Health and H2020 FET open (2x). He holds a number of patents in the field of heparan sulfates/glycosaminoglycans (e.g. JP2007-2562L7; US 2010/0061934 A1; US 6,180,769 B1).